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KMID : 1143320190080040007
Therapeutic Science for Neurorehabilitation
2019 Volume.8 No. 4 p.7 ~ p.18
Impact of Transcranial Direct Current Stimulation Combined With Constraint-Induced Movement Therapy on Upper Limb Function in Chronic Stroke: A Systematic Review
Kim Sun-Ho

Abstract
Objective : This systematic review aimed to investigate the impact of transcranial direct current stimulation combined with constraint-induced movement therapy (CIMT) in patients with stroke

Methods : PubMed and NDSL databases were employed to review literature published between January 2009 and December 2018. The main search terms were ¡°Transcranial direct current stimulation¡± or ¡°tDCS,¡± ¡°Constraint-induced movement therapy¡± or ¡°CIMT,¡± ¡°Upper extremity function,¡± ¡°Upper limb,¡± and ¡°Stroke.¡± Based on the inclusion and exclusion criteria, 6 articles were selected. Furthermore, intervention effects on upper extremity function, activities of daily living, and cortical activity were assessed.

Results : The current intensity, application time, and protocol of the CIMT varied the between studies. However, the intervention procedures to perform CIMT immediately after transcranial direct current stimulation was the same. Transcranial direct current stimulation combined with CIMT was effective in improving upper limb function and activities of daily living in patients with stoke and had a significant effect on cerebral cortex activation.

Conclusions : This study provides information on transcranial direct current stimulation combined with CIMT for use by clinical therapists. Further studies are needed to standardize the stimulation time, current intensity, and electrode attachment position. Furthermore, randomized controlled trials, including long-term follow up, are needed for larger populations using the most appropriate CIMT protocol.
KEYWORD
Cerebral cortex, Constraint-induced movement therapy, Stroke, Transcranial direct current stimulation, Upper limb function
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